In the mid-1980s, Isaak and his friends secured a record deal and began recording their unique brand of southwestern retro-pop under the moniker Silvertone. It was director Jonathan Demme -- already a fan of Isaak's music -- who gave him bit parts in 1988's Married to the Mob and Demme's 1991 breakthrough, The Silence of the Lambs. Though Isaak's acting career was slowly gaining momentum, his Roy Orbison-influenced ballads still weren't catching on with the general public. When David Lynch featured the jilted-lover anthem "Wicked Game" in his road movie Wild at Heart, however, radio requests for the song quickly grew, and Isaak found himself with a top-ten hit by the end of 1990 -- well over a year since the track was originally released. Thanks to Herb Ritts' sultry video for the song, Isaak had become a reluctant sex symbol as well. Lynch would be the first to capitalize on Isaak's heightened public profile, casting him as Special Agent Chester Desmond in 1992's baffling, elliptical Twin Peaks: Fire Walk with Me.
Despite the film's lackluster box-office performance, director Bernardo Bertolucci took notice and gave Isaak a lead role in his fantasy-biopic Little Buddha. Though convincing as the stoic family man whose son is mysteriously believed to be the latest reincarnation of Buddha, the neophyte actor couldn't withstand the wellspring of negative critical response to the film, causing some wags to slight his work in it. Perhaps as a response, Isaak has maintained a low profile in features since Buddha, choosing instead to take distinctive supporting roles in period films such as That Thing You Do and Grace of My Heart, both in 1996. -- Michael Hastings, All Movie Guide